The Sharpless catalog is a list of 313 H II regions intended to be comprehensive north of declination −27°. The first edition was published in 1953 with 142 objects (Sh1), and the second and final version was published by US astronomer Stewart Sharpless in 1959 with 312 objects. Sharpless also includes some planetary nebulae and supernova remnants, in addition to H II regions.

A nebula is a distinct luminescent part of interstellar medium, which can consist of ionized, neutral, or molecular hydrogen and also cosmic dust. Nebulae are often star-forming regions, such as in the "Pillars of Creation" in the Eagle Nebula. In these regions, the formations of gas, dust, and other materials "clump" together to form denser regions, which attract further matter and eventually become dense enough to form stars. The remaining material is then thought to form planets and other planetary system objects.