The Shaw Prize refers to three annual awards presented by the Shaw Prize Foundation in the fields of astronomy, medicine and life sciences, and mathematical sciences. Established in 2002 in Hong Kong by Hong Kong entertainment mogul and philanthropist Run Run Shaw (邵逸夫), the awards honour "individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence." The prize has been described as the "Nobel of the East".

Sir Run Run Shaw, also known as Shao Yifu and Siu Yat-fu, was a Hong Kong businessman, filmmaker, and philanthropist. He was one of the foremost influential movie moguls in the East Asian and Hong Kong entertainment industry. He founded the Shaw Brothers Studio, one of the largest film production companies in Hong Kong, and TVB, the dominant television company in Hong Kong.