Shire Brook is a small stream in the south eastern part of the City of Sheffield in South Yorkshire, England. It rises in the suburb of Gleadless Townend and flows in a general easterly direction for 4 miles (6.5 km) to its confluence with the River Rother between Beighton and Woodhouse Mill. In the past the brook has been both the border of Yorkshire and Derbyshire and between the sees of Canterbury and York. The course of the stream has been influenced by human intervention in the 20th century with the brook being diverted underground and flowing through culverts on three occasions as it traverses locations which were formerly landfill sites and extensive railway sidings.

The River Rother, a waterway in the northern midlands of England, gives its name to the town of Rotherham and to the Rother Valley parliamentary constituency. It rises in Pilsley in Derbyshire and flows in a generally northwards direction through the centre of Chesterfield, where it feeds the Chesterfield Canal, and on through the Rother Valley Country Park and several districts of Sheffield before joining the River Don at Rotherham in Yorkshire. Historically, it powered mills, mainly corn or flour mills, but most had ceased to operate by the early 20th century, and few of the mill buildings survive.