Mitchell Shire is a local government area in the Hume region of Victoria, Australia, located North of Melbourne. It covers an area of 2,862 square kilometres (1,105 sq mi) and, in August 2024, had a projected population of 61,362. Larger towns include Beveridge, Broadford, Kilmore, Seymour, Tallarook, Pyalong and Wallan. It was formed in 1994 from the amalgamation of the Shire of Pyalong, the Shire of Kilmore, most of the Shire of Broadford, and parts of the Shire of McIvor and Rural City of Seymour.

The Hume is an economic rural region located in the north-eastern part of Victoria, Australia. Comprising an area in excess of 40,000 square kilometres (15,000 sq mi) with a population that has grown from 263,000 to 309,684, the Hume region includes the local government areas of Alpine Shire, Rural City of Benalla, City of Wodonga, City of Greater Shepparton, Shire of Indigo, Shire of Mansfield, Shire of Strathbogie, Shire of Towong and the Rural City of Wangaratta, and also includes five unincorporated areas encompassing the alpine ski resorts in the region.