The Shire of Quilpie is a local government area in South West Queensland, Australia. It covers an area of 67,415 square kilometres (26,029 sq mi), and its administrative centre is the town of Quilpie.

South West Queensland is a remote region in the Australian state of Queensland which covers 319,808 km2 (123,479 sq mi). The region lies to the south of Central West Queensland and west of the Darling Downs and includes the Maranoa district and parts of the Channel Country. The area is noted for its cattle grazing, cotton farming, opal mining and oil and gas deposits.