The men's ISSF 50 meter pistol was one of the thirteen shooting events at the 1988 Summer Olympics. It was the second Olympic free pistol competition to feature final shooting, after an abortive attempt in 1960. There were 43 competitors from 31 nations. Nations had been limited to two shooters each since the 1952 Games. The event was won by Sorin Babii of Romania, the nation's first victory in the event and first medal in free pistol since 1972. Ragnar Skanåker of Sweden repeated as silver medalist, the second man to earn three medals in the free pistol; four years later, he would become the first to win four medals. Soviet Igor Basinski took bronze.

South Korea was the host nation and competed as Korea at the 1988 Summer Olympics in Seoul. 401 competitors, 269 men and 132 women, took part in 218 events in 27 sports.