"When [Isaac] told Jacob, “Come closer that I may feel you, my son,” (Gen 27 21) he urinated onto his calves, and his heart became as soft as wax, and God assigned to him two angels, one on his right and one on his left, in order to hold him up by his elbows." Genesis Rabbah 65:19
The Shepherd of Hermas, or the Good Shepherd, 3rd century, Catacombs of Rome