Shullsburg is a city in Lafayette County, Wisconsin, United States. The population was 1,226 at the 2010 census. The city is adjacent to the Town of Shullsburg. Founded in 1827 it is one of the oldest settlements in Wisconsin. There are 34 buildings listed on the National Register of Historic Places on its historic Water Street Commercial District. It is located within the Midwestern Driftless Area and is known for its history of lead mining and its cheese industry.

Lafayette County, sometimes spelled La Fayette County, is a county located in the U.S. state of Wisconsin. It was part of the Wisconsin Territory at the time of its founding. As of the 2020 census, the population was 16,611. Its county seat is Darlington. The county was named in honor of the Marquis de Lafayette, the French general who rendered assistance to the Continental Army in the American Revolutionary War. The courthouse scenes from the 2009 film Public Enemies were filmed at the Lafayette County Courthouse in Darlington.