Sialic acid
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Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone. The term "sialic acid" was first introduced by Swedish biochemist Gunnar Blix in 1952. The most common member of this gr
How the influenza virus gets into the cell by endocytosis
Orthomyxoviridae
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Orthomyxoviridae is a family of negative-sense RNA viruses. It includes nine genera: Alphainfluenzavirus, Betainfluenzavirus, Gammainfluenzavirus, Deltainfluenzavirus, Isavirus, Mykissvirus, Quaranjav
Sialic acid
…that interact with vertebrates. Many viruses such as the Ad26 serotype of adenoviruses (Adenoviridae), rotaviruses (Reoviridae) and influenza viruses (Orthomyxoviridae) can use host-sialylated structures for binding to their target host cell. Sialic acids provide a good target for these viruses since they are highly…
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Illustration of influenza virus replication and genome. A) Replication and transcription of influenza A virus. B) Influenza A genome. C) Influenza B genome. D) Influenza C genome. Segments translate to polymerase (PB1, PB2, and PA), hemagglutinin (HA), neuramindase (NA), nucleoprotein (NP), membrane protein (M), and non-structural protein (NS).
Transcription of mRNAs initiated by viral polymerase using cap snatching
Genetic evolution of human and swine influenza viruses, 1918–2009