Sibley is a village in Jackson County, Missouri, United States. The population was 314 at the 2020 census. It is known as the home of Fort Osage National Historic Landmark. It is part of the Kansas City metropolitan area.

Fort Osage was an early 19th-century factory trading post run by the United States Government in western Missouri on the American frontier; it was located in present-day Sibley, Missouri. The Treaty of Fort Clark, signed with certain members of the Osage Nation in 1808, called for the United States to establish Fort Osage as a trading post and to protect the Osage from tribal enemies.