Sidney Prescott is a fictional character and the main protagonist of the Scream franchise. The character was created by Kevin Williamson and is portrayed by Canadian actress Neve Campbell. She first appeared in Scream (1996) followed by four sequels: Scream 2 (1997), Scream 3 (2000), Scream 4 (2011), and Scream (2022). She is set to return in the upcoming seventh film in the franchise. Until 2023's Scream VI, her character had appeared in each successive film in the series, her role initially that of the victim but growing into heroine where she personally confronts each killer and defeats them.

Scream is an American murder mystery and slasher franchise that includes six films, a television series, merchandise, and games. The first four films were directed by Wes Craven. The series was created by Kevin Williamson, who wrote the first two films and the fourth, and will return to direct the seventh film. Ehren Kruger wrote the third. The fifth and sixth installments were directed by Matt Bettinelli-Olpin and Tyler Gillett, with Guy Busick and James Vanderbilt serving as writers and Williamson returning as executive producer. Dimension Films produced the first four films. Spyglass Media Group took over the rights from the fifth film on with Paramount Pictures distributing. The film series has grossed over US$900 million at the global box office.