The siege of Lille was the salient operation of the 1708 campaign season during the War of the Spanish Succession. After an obstinate defence of 120 days, the French garrison surrendered the city and citadel of Lille, commanded by Marshal Boufflers, to the forces of the Duke of Marlborough and Prince Eugene.

The War of the Spanish Succession was a European great power conflict fought between 1701 and 1714. The immediate cause was the death of the childless Charles II of Spain in November 1700, which led to a struggle for control of the Spanish Empire. His nominated heir was Philip of Anjou, a grandson of Louis XIV of France, whose main backers were France and most of Spain. His rival, Archduke Charles of Austria, was supported by the Grand Alliance, whose primary members included the Holy Roman Empire, the Dutch Republic, and Great Britain. Significant related conflicts include the 1700 to 1721 Great Northern War, and Queen Anne's War in North America.