The siege of Tripolitsa or fall of Tripolitsa, also known as the Tripolitsa massacre, was an early victory of the revolutionary Greek forces in the summer of 1821 during the Greek War of Independence, which had begun earlier that year, against the Ottoman Empire. Tripolitsa was an important target, because it was the administrative center of the Ottomans in the Peloponnese.

Tripoli is a city in the central part of the Peloponnese, in Greece. It is the capital of the Peloponnese region as well as of the regional unit of Arcadia. The homonymous municipality had 44,165 inhabitants in 2021.