The siege of Yodfat was a 47-day siege by Roman forces of the Jewish town of Yodfat which took place in 67 CE, during the Great Revolt. Led by Roman General Vespasian and his son Titus, both future emperors, the siege ended with the sacking of the town, the deaths of most of its inhabitants and the enslavement of the rest. It was the second bloodiest battle of the revolt, surpassed only by the Siege of Jerusalem, and the longest except for Jerusalem and Masada. The siege was chronicled by Josephus, who had personally commanded the Jewish forces at Yodfat and was subsequently captured by the Romans.

The First Jewish–Roman War, sometimes called the Great Jewish Revolt, or The Jewish War, was the first of three major rebellions by the Jews against the Roman Empire fought in Roman-controlled Judea, resulting in the destruction of Jewish towns, the displacement of its people and the appropriation of land for Roman military use, as well as the destruction of the Jewish Temple and polity.