The Simulation Theory World Tour was a world concert tour by English rock band Muse, in support of their eighth studio album, Simulation Theory (2018). The tour began in Houston on 22 February 2019 and ended in Lima on 15 October 2019. Numerous acts appeared as the opening act, including Tom Morello, Walk the Moon, Nothing But Thieves and SWMRS.

Simulation Theory is the eighth studio album by English rock band Muse. It was released on 9 November 2018 through Warner Bros. Records and Helium-3. Muse co-produced the album with Rich Costey, Mike Elizondo, Shellback, and Timbaland. Following the darker themes of Muse's prior albums, Simulation Theory incorporates lighter influences from science fiction and 1980s pop culture, with extensive use of synthesisers. The contemporary political climate of the United States informed the lyrics.