Sirdaryo Region is one of the regions of Uzbekistan, located in the center of the country on the left bank of Syr Darya River. It borders with Kazakhstan, Tajikistan, Tashkent Region, and Jizzakh Region. It covers an area of 4,276 square kilometres (1,651 sq mi), and is mostly desert, with the Starving Steppe taking up a significant part of the region's area. The population is estimated to be 860,900 (2021).

Tashkent Region is a viloyat (region) of Uzbekistan, located in the northeastern part of the country, between the Syr Darya River and the Tien Shan Mountains. It borders Kyrgyzstan, Tajikistan, Sirdaryo Region and Namangan Region, as well as the city of Tashkent which is a region in its own right, forming an enclave entirely encircled by the territory of Tashkent Region. It covers an area of 15,250 km². The population is estimated 2,975,900 (2021). Its capital is the city of Nurafshon. Other cities are Angren, Olmaliq, Ohangaron, Bekabad, Chirchiq, Gʻazalkent, Keles, Parkent, Yangiabad, and Yangiyoʻl.