Sissonville is a census-designated place (CDP) in Kanawha County, West Virginia, United States, along the Pocatalico River. The population was 4,028 at the 2010 census. Sissonville is located within 14 miles of Charleston, the state capital.

Kanawha County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 180,745, making it West Virginia's most populous county. The county seat is Charleston, which is also the state capital and most populous city. Kanawha County is part of the Charleston, WV Metropolitan Statistical Area.