The Sixty Dome Mosque, is a mosque in Bagerhat, Bangladesh. It is a part of the Mosque City of Bagerhat, a UNESCO World Heritage Site. It is the largest mosque in Bangladesh from the sultanate period (1352–1576). It was built during the Bengal Sultanate by Khan Jahan Ali, the governor of the Sundarbans. It has been described as "one of the most impressive Muslim monuments in the whole of South Asia."

The Mosque City of Bagerhat is a UNESCO World Heritage Site in Bagerhat District, Bangladesh. It contains 360 mosques, public buildings, mausoleums, bridges, roads, water tanks and other public buildings constructed from baked brick. The mosques were built during the Bengal Sultanate in the 15th century, of which the Sixty Dome Mosque is the largest. Other mosques include the Singar Mosque, the Nine Dome Mosque, the Tomb of Khan Jahan, the Bibi Begni Mosque and the Ronvijoypur Mosque. The mosques were built during the governorship of Ulugh Khan Jahan, a Turkic military officer appointed as governor in the Sundarbans by Sultan Mahmud Shah of Bengal.