Skinwalkers is a 2006 action horror film. It was released in the United States by Lions Gate Entertainment and After Dark Films, and focuses on werewolves. Directed by James Isaac, it stars Jason Behr, Elias Koteas, Rhona Mitra, and Tom Jackson. The film was originally announced for theatrical release on December 1, 2006, but was delayed until August 10, 2007.

James Isaac was an American film director and visual effects supervisor.