The Skipjack class was a class of United States Navy nuclear submarines (SSNs) that entered service in 1959-61. This class was named after its lead boat, USS Skipjack. The new class introduced the teardrop hull and the S5W reactor to U.S. nuclear submarines. The Skipjacks were the fastest U.S. nuclear submarines until the Los Angeles-class submarines, the first of which entered service in 1974.

A nuclear submarine is a submarine powered by a nuclear reactor, but not necessarily nuclear-armed. Nuclear submarines have considerable performance advantages over "conventional" submarines. Nuclear propulsion, being completely independent of air, frees the submarine from the need to surface frequently, as is necessary for conventional submarines. The large amount of power generated by a nuclear reactor allows nuclear submarines to operate at high speed for long periods, and the long interval between refuelings grants a range virtually unlimited, making the only limits on voyage times being imposed by such factors as the need to restock food or other consumables.