Skyline Drive is a 105-mile (169 km) National Parkway that runs the entire length of the National Park Service's Shenandoah National Park in the Blue Ridge Mountains of Virginia, generally along the ridge of the mountains. The drive's northern terminus is at an intersection with U.S. Route 340 (US 340) near Front Royal, and the southern terminus is at an interchange with US 250 near Interstate 64 (I-64) in Rockfish Gap, where the road continues south as the Blue Ridge Parkway. The road has intermediate interchanges with US 211 in Thornton Gap and US 33 in Swift Run Gap. Skyline Drive is part of Virginia State Route 48, which also includes the Virginia portion of the Blue Ridge Parkway, but this designation is not signed.

A National Parkway is a designation for a protected area in the United States given to scenic roadways with a protected corridor of surrounding parkland. National Parkways often connect cultural or historic sites. The U.S. National Park Service manages the parkways.