The Slave River is a Canadian river that flows from the confluence of the Rivière des Rochers and Peace River in northeastern Alberta and runs into Great Slave Lake in the Northwest Territories. The river's name is thought to derive from the name for the Slavey group of the Dene First Nations, Deh Gah Gotʼine, in the Athabaskan languages. The Chipewyan had displaced other native people from this region.

The Peace River is a 1,923-kilometre-long (1,195 mi) river in Canada that originates in the Rocky Mountains of northern British Columbia and flows to the northeast through northern Alberta. The Peace River joins the Athabasca River in the Peace-Athabasca Delta to form the Slave River, a tributary of the Mackenzie River. The Finlay River, the main headwater of the Peace River, is regarded as the ultimate source of the Mackenzie River. The combined Finlay–Peace–Slave–Mackenzie river system is the 13th longest river system in the world.