Slither is a 2006 science fiction comedy horror film written and directed by James Gunn in his directorial debut. Produced by Paul Brooks and Eric Newman, the film stars Nathan Fillion, Elizabeth Banks, Tania Saulnier, Gregg Henry, and Michael Rooker. The film is set in a small town in South Carolina that becomes invaded by a malevolent alien parasite.

James Francis Gunn Jr. is an American filmmaker and studio executive. He began his career as a screenwriter in the mid-1990s, starting at Troma Entertainment with Tromeo and Juliet (1997). He then began working as a director, starting with the horror-comedy film Slither (2006), and moving to the superhero genre with Super (2010), Guardians of the Galaxy (2014), Guardians of the Galaxy Vol. 2 (2017), The Suicide Squad (2021), and Guardians of the Galaxy Vol. 3 (2023). In 2022, Warner Bros. Discovery hired Gunn and Peter Safran to become co-chairmen and co-CEOs of DC Studios. Under DC Studios, Gunn will co-produce and executive produce every film and television series under the upcoming DC Universe (DCU) media franchise alongside Safran, which will act as a soft-reboot of the DC Extended Universe (DCEU). He will also continue to write and direct various projects set in the DCU, including the upcoming film Superman (2025).