Snuff is a type of smokeless tobacco product made from finely ground or pulverized tobacco leaves. It is snorted or "sniffed" into the nasal cavity, delivering nicotine and a flavored scent to the user. Traditionally, it is sniffed or inhaled lightly after a pinch of snuff is either placed onto the back surface of the hand, held pinched between thumb and index finger, or held by a specially made "snuffing" device.

Nicotiana rustica, commonly known as Aztec tobacco or strong tobacco, is a rainforest plant in the family Solanaceae native to South America. It is a very potent variety of tobacco, containing up to nine times more nicotine than common species of Nicotiana such as Nicotiana tabacum. More specifically, N. rustica leaves have a nicotine content as high as 9%, whereas N. tabacum leaves contain about 1 to 3%. The high concentration of nicotine in its leaves makes it useful for producing pesticides, and it has a wide variety of uses specific to cultures around the world. However, N. rustica is no longer cultivated in North America, as N. tabacum has replaced it.