Soft laser desorption is laser desorption of large molecules that results in ionization without fragmentation. "Soft" in the context of ion formation means forming ions without breaking chemical bonds
A commercial NALDI target
Koichi Tanaka is a Japanese electrical engineer who shared the Nobel Prize in Chemistry in 2002 for developing a novel method for mass spectrometric analyses of biological macromolecules with John Ben
Koizumi Cabinet E-mail Magazine, No.81, February 6, 2003.
with Masatoshi Koshiba and Jun'ichirō Koizumi (at the Prime Minister's Official Residence on October 11, 2002)
Shimadzu LCMS-IT-TOF liquid chromatography mass spectrometer, used in the development of next-generation diagnostic methods for detecting disease-related proteins from blood samples.