Solomon Creek is a tributary of the Susquehanna River in Luzerne County, Pennsylvania, in the United States. It is approximately 8.8 miles (14.2 km) long and flows through Fairview Township, Hanover Township, and Wilkes-Barre. The creek is affected by acid mine drainage and has significant loads of iron, aluminum, and manganese. The creek's named tributaries are Spring Run, Sugar Notch Run, and Pine Creek. The Solomon Creek watershed is located in the Anthracite Valley section of the ridge-and-valley geographical province. Major rock formations in the watershed include the Mauch Chunk Formation, the Spechty Kopf Formation, and the Catskill Formation.

Luzerne County is a county in the Commonwealth of Pennsylvania. According to the United States Census Bureau, the county has a total area of 906 square miles (2,350 km2), of which 890 square miles (2,300 km2) is land and 16 square miles (41 km2) is water. It is Northeastern Pennsylvania's second-largest county by total area. As of the 2020 census, the population was 325,594, making it the most populous county in the northeastern part of the state. The county seat and most populous city is Wilkes-Barre. Other populous communities include Hazleton, Kingston, Nanticoke, and Pittston. Luzerne County is included in the Scranton–Wilkes-Barre–Hazleton Metropolitan Statistical Area, which has a total population of 555,426 as of 2017. The county is part of the Northeastern Pennsylvania region of the state.