Some of My Best Friends is an American sitcom television series created by Marc Cherry and Tony Vitale, that aired on CBS from February 28 until April 11, 2001. The series was inspired by the film Kiss Me, Guido. The show was cancelled after only five of the seven produced episodes had aired.

Tony Vitale is an American film director, screenwriter, film producer, and television producer. He is best known for the 1997 film Kiss Me, Guido. More recently, Vitale pioneered the use of Internet Protocol television (IPTV) technologies and broadcast TV programming to help create dedicated OTT streaming channels.