The Souris River or Mouse River is a river in central North America. Approximately 435 miles (700 km) in length, it drains about 23,600 square miles (61,100 km2) in Canada and the United States.

Melita is a town located in the south-western corner of the Canadian province of Manitoba. It is surrounded by the Municipality of Two Borders and occupies a bend of the Souris River. Graham Creek runs along the west side of town and into the Souris River. The population at the 2016 census was 1,042. It sits at the junction of Highways 3 and 83, approximately 320 km southwest of Winnipeg. Melita is known as the "Grasslands Bird Capital of Manitoba" and is located in Manitoba's banana belt.