The South Carolina Republican Party (SCGOP) is the state affiliate of the national Republican Party in South Carolina. It is one of two major political parties in the state, along with the South Carolina Democratic Party, and is the dominant party. Incumbent governor Henry McMaster, as well as senators Tim Scott and Lindsey Graham, are members of the Republican party. Graham has served since January 3, 2003, having been elected in 2002 and re-elected in 2008, 2014, and 2020; Tim Scott was appointed in 2013 by then-governor Nikki Haley, who is also a Republican.

The South Carolina Democratic Party is the affiliate of the Democratic Party in the U.S. state of South Carolina. It is headquartered in Columbia, South Carolina.