The South Region of Brazil is one of the five regions of Brazil. It includes the states of Paraná, Rio Grande do Sul, and Santa Catarina, and covers 576,409.6 square kilometres (222,553.0 sq mi), being the smallest region of the country, occupying only about 6.76% of the territory of Brazil. Its whole area is smaller than that of the state of Minas Gerais, in Southeast Brazil, for example or the whole metropolitan France.

Italian Brazilians are Brazilians of full or partial Italian descent, whose ancestors were Italians who emigrated to Brazil during the Italian diaspora, or more recent Italian-born people who've settled in Brazil. Italian Brazilians are the largest number of people with full or partial Italian ancestry outside Italy, with São Paulo being the most populous city with Italian ancestry in the world. Nowadays, it is possible to find millions of descendants of Italians, from the southeastern state of Minas Gerais to the southernmost state of Rio Grande do Sul, with the majority living in São Paulo state. Small southern Brazilian towns, such as Nova Veneza, have as much as 95% of their population of Italian descent.