Đông Nam Bộ is a region in Vietnam. This region includes one municipality, Ho Chi Minh City; and five provinces: Đồng Nai, Bình Dương, Bà Rịa–Vũng Tàu province, Bình Phước and Tây Ninh. The two south central provinces Ninh Thuận and Bình Thuận are sometimes seen as part of the Southeast region. This region is the most economically developed region in Vietnam. In 2006, this region contributed 148,000 billion VND out of 251,000 billion VND to the state budget. This region is also the most highly urbanized in the country with more than 50% people living in urban areas.

Ho Chi Minh City, commonly known as Saigon, is the most populous city in Vietnam, with a population of around 9.3 million in 2023. The city's geography is defined by rivers and canals, of which the eponymously-named Saigon River is the largest. As a municipality, Ho Chi Minh City consists of 16 urban districts, five rural districts, and one municipal city (sub-city). As the largest financial centre in Vietnam, Ho Chi Minh City has the highest gross regional domestic product out of all Vietnam provinces and municipalities, contributing around a quarter of the country's total GDP. Ho Chi Minh City's metropolitan area is ASEAN's 6th largest economy, also the biggest outside an ASEAN country capital.