Southern Orchards is an established neighborhood near the south side of Columbus, Ohio. It is located immediately southeast of downtown and is the 23rd most walkable neighborhood in Columbus with 3,538 residents. The neighborhood is the target of revitalization and beautification largely due to its anchor institution Nationwide Children's Hospital and a renewed interest in urban living in the city's core. Since 2008, more than 90 properties have been improved through the hospital’s Healthy Homes program and continued revitalization is occurring along the major streets of Livingston and Parsons Avenues as the city moves to reconnect downtown to its surrounding neighborhoods.

Columbus, the state capital and Ohio's largest city, has numerous neighborhoods within its city limits. Neighborhood names and boundaries are not officially defined. They may vary or change from time to time due to demographic and economic variables.