Soyuz TMA-4 was a Soyuz mission to the International Space Station (ISS) launched by a Soyuz FG launch vehicle. It was launched on April 19, 2004 (UTC) from Baikonur Cosmodrome. Gennady Padalka from Russia, Michael Fincke from the US and André Kuipers from the Netherlands were flown to the International Space Station. Kuipers returned to Earth 9 days later together with ISS crew 8 with the re-entry module of the Soyuz TMA-3, the other two stayed as ISS crew 9. The craft landed October 24, 2004 with Padalka, Fincke and Yuri Shargin aboard.

The Soyuz-FG launch vehicle was an improved version of the Soyuz-U from the R-7 family of rockets, designed and constructed by TsSKB-Progress in Samara, Russia. Guidance, navigation, and control system was developed and manufactured by "Polisvit" Special Design Bureau.