SpaceX CRS-20 (CRS-20), also known as SpaceX-20, was a Commercial Resupply Service mission to the International Space Station (ISS) launched on 7 March 2020. The mission was contracted by NASA and was flown by SpaceX using Dragon. This was SpaceX's last flight for Dragon 1 and concluded the NASA Commercial Resupply Services (CRS-1) contract extension.

Commercial Resupply Services (CRS) are a series of flights awarded by NASA for the delivery of cargo and supplies to the International Space Station (ISS) on commercially operated spacecraft. The first CRS contracts were signed in 2008 and awarded $1.6 billion to SpaceX for twelve cargo Dragon and $1.9 billion to Orbital Sciences for eight Cygnus flights, covering deliveries to 2016. The Falcon 9 and Antares rockets were also developed under the CRS program to deliver cargo spacecraft to the ISS.