SpaceX CRS-24, also known as SpX-24, was a Commercial Resupply Service mission to the International Space Station launched on 21 December 2021, at 10:07:08 UTC. The mission is contracted by NASA and is flown by SpaceX using a Cargo Dragon. This is the fourth flight for SpaceX under NASA's CRS Phase 2 contract awarded in January 2016.

Commercial Resupply Services (CRS) are a series of flights awarded by NASA for the delivery of cargo and supplies to the International Space Station (ISS) on commercially operated spacecraft. The first CRS contracts were signed in 2008 and awarded $1.6 billion to SpaceX for twelve cargo Dragon and $1.9 billion to Orbital Sciences for eight Cygnus flights, covering deliveries to 2016. The Falcon 9 and Antares rockets were also developed under the CRS program to deliver cargo spacecraft to the ISS.