The Spacing Guild is an organization in Frank Herbert's science fiction Dune universe that possesses a monopoly on interstellar travel and banking. Guild Navigators use the drug melange to achieve limited prescience, a form of precognition that allows them to successfully navigate "folded space" and safely guide enormous starships called heighliners across interstellar space instantaneously.

Dune is an American science fiction media franchise that originated with the 1965 novel Dune by Frank Herbert and has continued to add new publications. Dune is frequently described as the best-selling science fiction novel in history. It won the inaugural Nebula Award for Best Novel and the Hugo Award in 1966 and was later adapted into a 1984 film, a 2000 television miniseries, and a two-part film series with the first film in 2021 and a sequel in 2024. Herbert wrote five sequels, the first two of which were concomitantly adapted as a 2003 miniseries. Dune has also inspired tabletop games and a series of video games. Since 2009, the names of planets from the Dune novels have been adopted for the real-world nomenclature of plains and other features on Saturn's moon Titan.