The Spain women's national water polo team represents Spain in women's international water polo competitions and it is controlled by Real Federación Española de Natación.

Water polo has been part of the Summer Olympics program since the second games, in 1900. A women's water polo tournament was introduced for the 2000 Summer Olympics. Hungary has been the most successful country in men's tournament, while the United States is the only team to win multiple times at the women's tournament since its introduction. Italy is the first and only country to win both the men's and women's water polo tournaments.