The Spanish Golden Age was a period of flourishing in arts and literature in Spain, coinciding with the political rise of the Spanish Empire under the Catholic Monarchs of Spain and the Spanish Habsburgs. The greatest patron of Spanish art and culture during this period was King Philip II (1556–1598). His royal palace, El Escorial, invited the attention of some of Europe's greatest architects and painters, such as El Greco, who infused Spanish art with foreign styles and helped create a uniquely Spanish style of painting. The period is associated with the reigns of Isabella I, Ferdinand II, Charles V, Philip II, Philip III, and Philip IV, when Spain was at the peak of its power and influence in Europe and the world.

Habsburg Spain refers to Spain and the Spanish Empire, also known as the Catholic Monarchy, in the period from 1516 to 1700 when it was ruled by kings from the House of Habsburg. It had territories around the world, including modern-day Spain, a piece of south-eastern France, eventually Portugal and many other lands outside the Iberian Peninsula, like in the Americas. Habsburg Spain was a composite monarchy and a personal union. The Habsburg Spanish monarchs of this period are chiefly Charles I, Philip II, Philip III, Philip IV and Charles II. In this period the Spanish empire was at the zenith of its influence and power. Spain, or "the Spains", referring to Spanish territories across different continents in this period, initially covered the entire Iberian peninsula, including the crowns of Castile, Aragon and from 1580 Portugal. It then expanded to include territories over the five continents, consisting of much of the American continent and islands thereof, the West Indies in the Americas, the Low Countries, Belgium, Luxembourg, Italian territories and France in Europe, Portuguese possessions such as small enclaves like Ceuta and Oran in North Africa, and the Philippines and other possessions in Southeast Asia. The period of Spanish history has also been referred to as the "Age of Expansion".