Spanish Town is the capital and the largest town in the parish of St. Catherine in the historic county of Middlesex, Jamaica. It was the Spanish and British capital of Jamaica from 1534 until 1872. The town is home to numerous memorials, the national archives, and one of the oldest Anglican churches outside England.

Saint Catherine is a parish in the south east of Jamaica. It is located in the county of Middlesex, and is one of the island's largest and most economically valued parishes because of its many resources. It includes the first capital of Jamaica, Spanish Town, originally known as San Jago de la Vega or Santiago de la Vega.