Don Antonio de Ulloa was a Velasco-class unprotected cruiser of the Spanish Navy that fought in the Battle of Manila Bay during the Spanish–American War. She was built at La Carraca shipyard, Cadiz, Spain. Her keel was laid in 1883 and the vessel was launched on 23 January 1887. Don Antonio de Ulloa took an active part in Spanish military action against Philippine insurgents during the "Tagalog Revolt" (1896–1897), the Spanish name for the first two years of the Philippine Revolution. During her overhaul in Manila bay whilst part of the squadron of Rear Admiral Patricio Montojo y Pasarón, the Battle of Manila Bay occurred. With her reduced complement, armament, and inability to maneuver she was sunk with little resistance.

The Velasco class of unprotected cruisers was a series of eight cruisers built during the 1880s for service with the Spanish Navy. They were named after Luis Vicente de Velasco.