Speedball, powerball, or over and under is the polydrug mixture of a stimulant with a depressant, usually an opioid. The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl. A speedball may be taken intravenously or by nasal insufflation.

Steven Adler is an American musician. He is the former drummer and co-songwriter of the hard rock band Guns N' Roses, with whom he achieved worldwide success in the late 1980s.