Spencer County is a county located in the U.S. state of Indiana. As of the 2020 census, the population was 19,810. The county seat is Rockport. Despite not being in the Owensboro Metropolitan Area, the entire riverfront of the city of Owensboro, Kentucky borders the southern tip of the county.

Rockport is a city in Ohio Township and the county seat of Spencer County, Indiana, along the Ohio River. The population was 2,270 at the 2010 census. Once the largest community in Spencer County, the city has recently been surpassed by the town of Santa Claus. At 37°53'1" north, Rockport is also the southernmost city in the state, located slightly south of Evansville, Cannelton, or Mount Vernon.