Spencer Horatio Walpole was a British Conservative Party politician who served three times as Home Secretary in the administrations of Lord Derby.

The Secretary of State for the Home Department, more commonly known as the Home Secretary, is a senior minister of the Crown in the Government of the United Kingdom and the head of the Home Office. The position is a Great Office of State, making the home secretary one of the most senior and influential ministers in the government. The incumbent is a statutory member of the British Cabinet and National Security Council.