Spencer Williams was an American actor and filmmaker. He portrayed Andy on TV's The Amos 'n' Andy Show and directed films including the 1941 race film The Blood of Jesus. Williams was a pioneering African-American film producer and director.

Amos 'n' Andy was an American radio sitcom about black characters, initially set in Chicago then later in the Harlem section of New York City. While the show had a brief life on 1950s television with black actors, the 1928 to 1960 radio show was created, written and voiced by two white actors, Freeman Gosden and Charles Correll, who played Amos Jones (Gosden) and Andrew Hogg Brown (Correll), as well as incidental characters. On television, 1951–1953, black actors took over the majority of the roles; white characters were infrequent.