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Spliceosomal splicing cycle
Spliceosomal splicing cycle
Figure 1. Above are electron microscopy fields of negatively stained yeast (Saccharomyces cerevisiae) tri-snRNPs. Below left is a schematic illustrati
Figure 1. Above are electron microscopy fields of negatively stained yeast (Saccharomyces cerevisiae) tri-snRNPs. Below left is a schematic illustration of the interaction of tri-snRNP proteins with the U4/U6 snRNA duplex. Below right is a cartoon model of the yeast tri-snRNP with shaded areas corresponding to U5 (gray), U4/U6 (orange) and the linker region (yellow).
A comparison between major and minor splicing mechanisms
A comparison between major and minor splicing mechanisms
U1 and U11 can be folded similarly
U1 and U11 can be folded similarly