Spotswood railway station is located on the Werribee and Williamstown lines in Victoria, Australia. It serves the western Melbourne suburb of Spotswood, and opened on 1 December 1878 as Edom. It was renamed Bayswater on 1 September 1881, renamed Spottiswoode on 1 October of that year, and renamed Spotswood on 1 August 1905.

The Werribee line is a commuter railway line in the city of Melbourne, Victoria, Australia. Operated by Metro Trains Melbourne, it is the city's ninth longest metropolitan railway line at 32.9 kilometres (20.4 mi). The line runs from Flinders Street station in central Melbourne to Werribee station in the south west, serving 17 stations via Footscray, Newport, and Altona. The line operates for approximately 19 hours a day with 24 hour service available on Friday and Saturday nights. During peak hour, headways of up to 5–20 minutes are operated with services every 20–30 minutes during off-peak hours. Trains on the Werribee line run with a two three-car formations of Comeng, Siemens Nexas, and X'Trapolis 100 trainsets.