Sprague is a town in New London County, Connecticut, United States. The town is part of the Southeastern Connecticut Planning Region. The town was named after William Sprague III, who laid out the industrial section. The population was 2,967 at the 2020 census. Sprague includes three villages: Baltic, Hanover, and Versailles.

New London County is in the southeastern corner of Connecticut and comprises the Norwich-New London, Connecticut Metropolitan Statistical Area, which is also included in the Hartford-East Hartford, Connecticut Combined Statistical Area. There is no county government and no county seat, as is the case with all eight of Connecticut's counties; towns are responsible for all local government activities, including fire and rescue, snow removal, and schools.