Sprague Avenue is a major east–west street serving Spokane, Spokane Valley, and Liberty Lake, Washington, United States. It travels approximately 17 miles (27 km), extending from Downtown Spokane eastward through Spokane Valley as an arterial road, and continues on as a collector road to its eastern terminus in Liberty Lake.

Spokane Valley is a city in Spokane County, Washington, United States, and the largest suburb of Spokane. It is located east of Spokane, west of Coeur d'Alene, Idaho, and surrounds the city of Millwood on three sides. The city incorporated as the City of Spokane Valley on March 31, 2003. The population was 102,976 at the 2020 census, making it the eighth-largest city in Washington state. Spokane Valley is named after the valley of the Spokane River, in which it is located. The city and the general area is colloquially referred to as "The Valley" by residents of the Spokane–Coeur d'Alene area.