The Spree Forest is a large inland delta of the river Spree, and a historical cultural landscape located in the region of (Lower) Lusatia, in the state of Brandenburg, Germany, about 100 km southeast of Berlin and close to the city of Cottbus. The Spree Forest is located within the settlement area of the (Lower) Sorbs, and the region is officially bilingual, German and Lower Sorbian.

The Spree is, with a length of approximately 400 kilometres (250 mi), the main tributary of the River Havel. The Spree is much longer than the Havel, which it flows into at Berlin-Spandau; the Havel then flows into the Elbe at Havelberg. The river rises in the Lusatian Highlands, that are part of the Sudetes, in the Lusatian part of Saxony, where it has three sources: the historical one called Spreeborn in the village of Spreedorf, the water-richest one in Neugersdorf, and the highest elevated one in Eibau. The Spree then flows northwards through Upper and Lower Lusatia, where it crosses the border between Saxony and Brandenburg. After passing through Cottbus, it forms the Spree Forest, a large inland delta and biosphere reserve. It then flows through Lake Schwielochsee before entering Berlin, as Müggelspree (pronounced [ˈmʏɡl̩ˌʃpʁeː] ).