Highway 16 is a provincial highway in the Canadian province of Saskatchewan. It is the Saskatchewan section of the Yellowhead Highway, and also the Trans-Canada Highway Yellowhead section. The main purpose of this highway is to connect Saskatchewan with Canadian cities such as Edmonton and Winnipeg. The highway runs from the Alberta boundary in Lloydminster to the Manitoba boundary near Marchwell. Major cities it passes through are Saskatoon, North Battleford in the central part of the province, Yorkton in the far east and Lloydminster to the far west.